SkinMedica TNS Advanced+ Serum Review | SkinSourcer

The Shelf · Counter Culture: What the Clinic Counter Sells, With the Lists Read

SkinMedica TNS Advanced+ Serum
No. 07 in Edit 046

SkinMedica TNS Advanced+ Serum

Serums USA Approx. $295

The most famous serum in this whole category and the one people mean when they say they use a growth factor serum. The dual chamber pump is the real design idea: the two textures stay separate until the moment you use them. The list reads as advertised, human fibroblast conditioned media in first position after water and glycols, with a dimer tripeptide, whey protein and a chlorella extract behind it, and no parfum anywhere, which confirms the brand's fragrance free claim rather than just repeating it. At two hundred and ninety five dollars it is the most expensive thing here.

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Why we like the TNS Advanced+ Serum

  • The dual chamber pump is a genuinely good piece of packaging
  • Fragrance-free, confirmed against the published list
  • The conditioned media sits high in the list, not at the bottom
  • One step, so the routine around it can stay simple
Texture
Two chambers you pump together, one thin and one thick, and the mixed result is a light lotion
Key ingredients
Human fibroblast conditioned media · Dimer tripeptide-43 · Whey protein · Chlorella vulgaris extract · Apple fruit extract · Vitamin E (tocopheryl acetate)
Fragrance
Fragrance-free. No parfum in the published ingredient list, which now confirms the brand's own statement.
Skin type
Mature · Textured
Best for
Anyone who was already using TNS Essential · Evening · A single expensive step rather than five cheap ones
Works on
Fine lines · Loss of firmness · Skin texture
Made in
USA
Where to buy
Dermstore
Price when checked
$295 on 2026-09-09
Listing checked
2026-09-03

Our verdict on the SkinMedica TNS Advanced+ Serum

The famous one. Priced like it knows that.

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Reviewed 2026-08-22. SkinMedica TNS Advanced+ Serum appears in Counter Culture: What the Clinic Counter Sells, With the Lists Read. Every product on The Shelf is listed in the product index.